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Traditional Chinese medicine to prevent SARS at Shenzhen Pinghu People's Hospital
Prevention based on syndrome differentiation and three factors: Experience and reflection on the application of traditional Chinese medicine to prevent SARS at Shenzhen Pinghu People's Hospital
TCM medicinal formulas were used to prevent SARS in 2003 at Pinghu People's Hospital in Zhejiang Province, China.
For both staff and patients admitted to the hospital, the MTC decoction for prevention was provided free of charge, and about 500 people took it every day.
Prevention drugs were also recommended to many companies in Pinghu City, with a total of more than 150,000 people taking the drug. The follow-up survey showed that there were no cases of fever.
Resultados de tradução_border
Lianhua Qingwen & Korona
Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: A multicenter, prospective, randomized controlled trial
Lianhua Qingwen, patented and marketed for the severe acute respiratory syndrome (SARS) epidemic since 2003 in China, can significantly reduce the duration of fever, fatigue and cough.
“LH capsules confer therapeutic effects on Covid-19, improving the rate of recovery from symptoms, shortening recovery time and improving recovery from chest radiological abnormalities. In light of the efficacy and safety profiles, LH capsules may be considered for the treatment of Covid-19.”
Hu K., Guan W., Bi Y., et al. Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: a multicenter, prospective, randomized controlled trial. Phytomedicine. 2020:153242. doi: 10.1016/j.phymed.2020.153242
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066964/#bib45
Traditional Chinese Medicine is effective for COVID-19
Traditional Chinese Medicine is effective for COVID-19: A systematic review and meta-analysis
The study showed that the COVID-19 can be treated effectively by TCM medicinal formulae combining with conventional treatment, in comparison with the pure conventional treatment.
"The advantages of the TCM medicine are effective, cheap, preventive, and personalized, particularly it can be promptly improved according to the change of pandemic pattern. These characteristics of the TCM medicine are particularly important for current situation that the effective anti-virus drugs are still not available yet", according to authors.
Xu J, Liu H, Fan Y, Ji B. Traditional Chinese Medicine is effective for COVID-19: A systematic review and meta-analysis. Med Nov Technol Devices. 2022;16:100139. doi:10.1016/j.medntd.2022.100139
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066964/#bib45
Experiência da medicina tradicional chinesa para prevenir a SARS no Hospital Popular de Shenzhen
A experiência da medicina tradicional chinesa para prevenir a SARS no Hospital Popular de Shenzhen Pinghu e reflexões sobre problemas relacionados
Hu WeidongYang HaomingZheng Gaoping
Sunday, 22 May 2022
Phyto promise for Ebola
Compound from Chinese medicinal herb shows promise for Ebola
WASHINGTON (Reuters) - A drug derived from a Chinese medicinal herb is showing promise for combating Ebola infection, effectively imprisoning the virus inside cells so it cannot do its usual damage, scientists said on Thursday.
The researchers said the compound, called tetrandrine, blocked infection of human white blood cells in lab dishes and prevented Ebola virus disease in lab mice. More research is needed, including monkey studies, before it can be tested in people, they added.
“The work has revealed a new chink in the armor of Ebola virus,” said virologist Robert Davey of the Texas Biomedical Research Institute in San Antonio, who estimated this approach potentially could be used to treat people in two to five years.
“I am hopeful that the dose needed to control disease will be safe but we just have to do the work and find out,” Davey added.
There is no approved drug treatment or vaccine for the Ebola virus, which causes hemorrhagic fever and spreads person to person through contact with body fluids.
“In my opinion, tetrandrine is now one of the most promising candidates that could be used to inhibit Ebola virus infection,” said Norbert Klugbauer, a pharmacologist and microbiologist at Germany’s University of Freiburg who also worked on the study published in the journal Science.
To successfully infect a cell, the virus needs to be transported deep within it in order to break out of bubble-like intracellular transport structures called endosomes that carry the virus within the cell.
The researchers identified channels that are important in controlling the movement of the “bubbles” within cells. These are known as “two-pore channels.” The study showed that tetrandrine blocked these channels, effectively imprisoning the virus inside the “bubbles” so it could not actually infect the cell.
“The virus is then trapped in the bubble and cannot escape. It is then detoured to be destroyed. This stops infection,” Davey said.
In human cells in lab dishes, the researchers found tetrandrine inhibited infection by the virus of white blood cells called macrophages. These cells are important players in the immune system’s ability to ward off foreign invaders like viruses and bacteria, basically swallowing them up.
Tetrandrine is derived from the root of a medicinal herb, Stephania tetrandra. It also lowers blood pressure.
More than 9,500 deaths have been reported in three West African countries since the world’s worst Ebola outbreak began in December 2013.
Reporting by Will Dunham; Editing by Mohammad Zargham
By Will Dunham REUTERS
https://www.reuters.com/article/us-health-ebola-treatment-idUSKBN0LU2ET20150226